Affinity DataKi: 3nM ΔG°: -12.1kcal/molepH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of human recombinant 17beta-HSD1 expressed in HEK293 cell lysate assessed as conversion of radiolabeled estrone to estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Inhibition of (unknown origin) 17beta-HSD1 assessed as conversion of [14C]estradiol to [14C]estrone using NADP+More data for this Ligand-Target Pair
Affinity DataKi: 2.80E+3nMAssay Description:Tested by protection experiments to demonstrate the inactivation of estradiol dehydrogenase and the kinetic parameter Ki app was reported at a concen...More data for this Ligand-Target Pair
Affinity DataKi: 4.08E+3nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataKi: 9.50E+3nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataKi: 1.28E+4nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.40E+4nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataKi: 5.90E+4nMAssay Description:Tested for time-dependent inactivation of the enzyme that followed pseudo- first- order kinetics in the absence of NAD+ and the Ki values were report...More data for this Ligand-Target Pair
Affinity DataKi: 6.50E+4nMAssay Description:Tested for time-dependent inactivation of the enzyme that followed pseudo- first- order kinetics in the absence of NAD+ and the Ki values were report...More data for this Ligand-Target Pair
Affinity DataKi: 6.94E+4nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair
Affinity DataKi: 2.50E+5nM ΔG°: -5.11kcal/molepH: 7.5 T: 2°CAssay Description:For steady-state kinetic study of hybrid inhibitors, a Fluorolog 3 instrument was used to monitor the fluorescent signal of NADPH formed during estra...More data for this Ligand-Target Pair
Affinity DataKi: 4.25E+5nMAssay Description:Inhibition of human estradiol 17beta-dehydrogenaseMore data for this Ligand-Target Pair