Compile Data Set for Download or QSAR
maximum 50k data
Found 22 Enz. Inhib. hit(s) with all data for entry = 2809
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24933(2-amino-isoxazolopyridine, 9 | 3-(2H-1,3-benzodiox...)
Affinity DataIC50:  4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24933(2-amino-isoxazolopyridine, 9 | 3-(2H-1,3-benzodiox...)
Affinity DataIC50:  24nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24935(2-amino-isoxazolopyridine, 15 | 3-[3-chloro-5-(5-{...)
Affinity DataIC50:  51nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24934(2-amino-isoxazolopyridine, 13 | 3-[3-chloro-5-(5-{...)
Affinity DataIC50:  99nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24926(1-(3-chlorophenyl)-3-methyl-N-[(1S)-1-phenylethyl]...)
Affinity DataIC50:  121nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24935(2-amino-isoxazolopyridine, 15 | 3-[3-chloro-5-(5-{...)
Affinity DataIC50:  172nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24933(2-amino-isoxazolopyridine, 9 | 3-(2H-1,3-benzodiox...)
Affinity DataIC50:  214nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24930(2-amino-isoxazolopyridine, 6 | 3-(3,5-dimethylphen...)
Affinity DataIC50:  330nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24928(2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...)
Affinity DataIC50:  549nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24931(2-amino-isoxazolopyridine, 7 | 3-(3-chlorophenyl)-...)
Affinity DataIC50:  625nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24938(2-amino-isoxazolopyridine, 20 | 3-(4-methylthiophe...)
Affinity DataIC50:  779nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24929(2-amino-isoxazolopyridine, 5 | 3-(4-methylphenyl)-...)
Affinity DataIC50:  1.17E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24925(3-methyl-1-phenyl-N-[(1S)-1-phenylethyl]-1H-pyrazo...)
Affinity DataIC50:  1.30E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24935(2-amino-isoxazolopyridine, 15 | 3-[3-chloro-5-(5-{...)
Affinity DataIC50:  1.38E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK2(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24928(2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...)
Affinity DataIC50:  1.45E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24927(2-amino-isoxazolopyridine, 3 | 3-phenyl-N-[(1S)-1-...)
Affinity DataIC50:  1.62E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24937(2-amino-isoxazolopyridine, 19 | N-[(1S)-1-phenylet...)
Affinity DataIC50:  3.01E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24932(2-amino-isoxazolopyridine, 8 | 3-(3,4-dimethoxyphe...)
Affinity DataIC50:  4.93E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24939(2-amino-isoxazolopyridine, 21 | 3-(2-methylcyclohe...)
Affinity DataIC50:  5.69E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24940(2-amino-isoxazolopyridine, 23 | 3-[3-(5-{[(1S)-1-p...)
Affinity DataIC50:  7.48E+3nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK3(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24928(2-amino-isoxazolopyridine, 4 | 3-(3-methylphenyl)-...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Sunesis Pharmaceuticals

LigandPNGBDBM24936(2-amino-isoxazolopyridine, 18 | 3-benzyl-N-[(1S)-1...)
Affinity DataIC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:An IMAP fluorescence polarization-based assay format (Molecular Devices) was used to determine the ability of compounds to inhibit the phosphorylatio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed