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Found 12 Enz. Inhib. hit(s) with all data for entry = 50016821
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597526(CHEMBL5187166)
Affinity DataIC50:  1.29E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50:  1.32E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597525(CHEMBL5202371)
Affinity DataIC50:  3.22E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597524(CHEMBL5173553)
Affinity DataIC50:  3.97E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597523(CHEMBL1091913)
Affinity DataIC50:  7.71E+4nMAssay Description:Inhibition of full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS by isothermal titration calorimetry ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597525(CHEMBL5202371)
Affinity DataKd:  1.05E+4nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597524(CHEMBL5173553)
Affinity DataKd:  1.04E+4nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597523(CHEMBL1091913)
Affinity DataKd:  1.14E+4nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataKd:  7.50E+3nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | CHEMBL418052 | S-(5'-adenosyl)-L-homocyst...)
Affinity DataKd:  1.36E+4nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
TargettRNA (cytosine(38)-C(5))-methyltransferase(Homo sapiens)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50597526(CHEMBL5187166)
Affinity DataKd:  8.10E+3nMAssay Description:Binding affinity to full length human N-terminal his6-tagged DNMT2 expressed in Escherichia coli Rosetta2(DE3)pLysS assessed as dissociation constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed