Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50018507
LigandPNGBDBM50608974(CHEMBL5288856)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608972(CHEMBL5266334)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608973(CHEMBL4563588)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))TBA
LigandPNGBDBM50035620(CHEMBL3338445)
Affinity DataIC50:  0.160nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50608971(CHEMBL5290355)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608964(CHEMBL5271175)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM290889(1-[2-fluoro-4- (tetrahydro-2H- pyran-4-yl)phenyl]-...)
Affinity DataIC50:  0.770nMAssay Description:Inhibition of PDE10A (unknown origin) by scintillation proximity assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM290889(1-[2-fluoro-4- (tetrahydro-2H- pyran-4-yl)phenyl]-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE10A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608970(CHEMBL5284754)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50365964(CHEMBL1956235 | CHEMBL2070530)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50520336(CHEMBL4470042)
Affinity DataIC50:  2nMAssay Description:Inhibition of human PDE10A (449 to 789 residues) expressed in Escherichia coli BL21(DE3) using cAMP as substrate incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM31604(methyl substituted pyrazole, 25)
Affinity DataIC50:  5.10nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50405611(CHEMBL5273419)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50608965(CHEMBL5276744)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608975(CHEMBL5266740)
Affinity DataIC50:  9.70nMAssay Description:Inhibition of PDE10A2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50003995(CHEMBL2180009)
Affinity DataIC50:  12nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50405608(CHEMBL5274332)
Affinity DataIC50:  22nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
LigandPNGBDBM50608966(CHEMBL5277377)
Affinity DataIC50:  29nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608962(CHEMBL5288169)
Affinity DataIC50:  44nMAssay Description:Inhibition of human PDE10A (449 to 789 residues) expressed in Escherichia coli BL21(DE3) using cAMP as substrate incubated for 30 mins by HTRF analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50608969(CHEMBL5280875)
Affinity DataIC50:  52nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50608968(CHEMBL5274729)
Affinity DataIC50:  112nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50035620(CHEMBL3338445)
Affinity DataIC50:  280nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
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LigandPNGBDBM50608963(CHEMBL563605)
Affinity DataIC50:  371nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM50608967(CHEMBL5287145)
Affinity DataIC50:  500nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50496800(CHEMBL3218036)
Affinity DataKd:  1.30nMAssay Description:Binding affinity to PDE10A in rat striatum homogenateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM290889(1-[2-fluoro-4- (tetrahydro-2H- pyran-4-yl)phenyl]-...)
Affinity DataKd:  12nMAssay Description:Binding affinity to PDE10A in rat brain caudate-putamen by saturation binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM290889(1-[2-fluoro-4- (tetrahydro-2H- pyran-4-yl)phenyl]-...)
Affinity DataKd:  4.70nMAssay Description:Binding affinity to PDE10A in rat brain nucleus accumbens by saturation binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed