Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50046937
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
Affinity DataKi: 11nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [125I] alpha bungarotoxin from human alpha7 nACh receptor incubated for 20 secsMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 30nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 67nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 71nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 77nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 80nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 92nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 107nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 108nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 127nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 155nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 194nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
Affinity DataKi: 204nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 343nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 384nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 394nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 429nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 609nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 680nMAssay Description:Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 744nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 821nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 1.45E+3nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 1.77E+3nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 1.80E+3nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 2.04E+3nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 2.08E+3nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 2.37E+3nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
Affinity DataKi: 2.40E+3nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 3.79E+3nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 5.02E+3nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
Affinity DataKi: 9.30E+3nMAssay Description:Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 1.15E+4nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 1.88E+4nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 3.20E+4nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKi: 3.50E+4nMAssay Description:Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKd: 0.300nMAssay Description:Binding affinity to alpha3beta4 nACh receptor (unknown origin) expressed in Xenopus oocytesMore data for this Ligand-Target Pair
Affinity DataEC50: 6.00E+4nMAssay Description:Agonist activity at human alpha7 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes after 2 to 3 days by patch cla...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 2.00E+4nMAssay Description:Agonist activity at human alpha3beta4 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes after 2 to 3 days by patc...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataKd: 0.0300nMAssay Description:Binding affinity to alpha4beta2 nACh receptor (unknown origin) expressed in Xenopus oocytesMore data for this Ligand-Target Pair