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Found 6 Enz. Inhib. hit(s) with Target = 'Fructose-1,6-bisphosphatase 1' and Ligand = 'BDBM50305589'
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of FBPase in human liver using fructose-2,6phosphate as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of FBPase in human liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of FBPase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataIC50:  5.79E+3nMAssay Description:Inhibition of mouse liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB

TargetFructose-1,6-bisphosphatase 1(Mus musculus)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50305589(CHEMBL595149 | N-(5-bromothiazol-2-ylcarbamoyl)-3-...)
Affinity DataEC50:  4.90E+4nMAssay Description:Inhibition of FBPase in mouse liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedMMDB