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Found 4 Enz. Inhib. hit(s) with Target = 'Sphingosine 1-phosphate receptor 1' and Ligand = 'BDBM450730'
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50:  6.67nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50:  6.70nMAssay Description:Inhibition of S1PR1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50:  6.70nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSphingosine 1-phosphate receptor 1(Homo sapiens (Human))
Washington University

US Patent
LigandPNGBDBM450730(US10676467, Compound 8c | US10676467, Compound TZ ...)
Affinity DataIC50:  6.70nMAssay Description:Newly synthesized compounds were first evaluated for binding potency toward S1P1 by a [32P]S1P competitive binding assay following published procedur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent