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TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 6.20nMAssay Description:Binding affinity to recombinant human His-tagged STING by measuring fluorescent signals in the presence of d2 labelled STING wild type ligand by HTRF...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 2.00E+4nMAssay Description:Agonist activity to C-terminal domain human STING (139 to 379 residues)More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 1.23E+3nMAssay Description:Agonist activity at STING in human wild-type THP1-Dual cells co-expressing ISRE reporter assessed as IRF-mediated immune response incubated for 24 hr...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKd: 1.60nMAssay Description:Binding affinity to human C-terminal domain STING (139 to 379 residues) assessed as dissociation constant by scanning fluorimetry assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity to C-terminal domain STING (139 to 379 residues) in human PBMC assessed as IFN-beta secretionMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataKd: 1.60nMAssay Description:Binding affinity to human wild type STING assessed as dissociation constantMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Induction of STING in human PBMC assessed as increase in IFNbeta secretionMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Inhibition of wild type human STING by SPA assayMore data for this Ligand-Target Pair
TargetStimulator of interferon genes protein(Human)
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Korea Research Institute Of Chemical Technology
Curated by ChEMBL
Affinity DataEC50: 3.10E+3nMAssay Description:Agonist activity at human wild type STINGMore data for this Ligand-Target Pair
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