Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1/JAK2' and Ligand = 'BDBM50583442'
TargetTyrosine-protein kinase JAK1/JAK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Sichuan University And Collaborative Innovation Center Of Biotherapy
Curated by ChEMBL
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of JAK1/JAK2 signalling in human PBMC assessed as inhibition of IL-27 stimulated phosphorylation of STAT3 preincubated for 60 mins followe...More data for this Ligand-Target Pair