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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1/JAK2' and Ligand = 'BDBM50583442'
TargetTyrosine-protein kinase JAK1/JAK2(Homo sapiens (Human))
Sichuan University And Collaborative Innovation Center Of Biotherapy

Curated by ChEMBL
LigandPNGBDBM50583442(CHEMBL5077096)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of JAK1/JAK2 signalling in human PBMC assessed as inhibition of IL-27 stimulated phosphorylation of STAT3 preincubated for 60 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed