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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM648237'
Target
Tyrosine-protein kinase JAK1
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM648237
(US11884671, Example 14)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
JAK1: The 2×JAK/Tyr 06 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02%...
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Target Info
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Ligand Info
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Details
US Patent
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