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Found
1
Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3 [512-1124]' and Ligand = 'BDBM493075'
Target
Tyrosine-protein kinase JAK3 [512-1124]
(Homo sapiens (Human))
Janssen Pharmaceutica
US Patent
Ligand
BDBM493075
(2-((1r,4r)-4-(2-(2H-1,2,3-Triazol-4-yl)imidazo[4,5...)
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Affinity Data
IC50: 37.7nM
Assay Description:
11-point dosing series were made for each compound by serially diluting 1:3 or 1:4 in DMSO, with point 12 being a DMSO control. From the serial dilut...
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Ligand Info
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