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Found 4 of ic50 for monomerid = 31197
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataIC50:  105nMAssay Description:Binding affinity to MDM2 in human U87MG cells assessed as inhibition of MDM2/p53 protein interaction after 10 mins by quantitative sandwich immuno as...More data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataIC50:  180nMAssay Description:Inhibition of GST-tagged MDM2 binding to p53 by ELISAMore data for this Ligand-Target Pair
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University Of Pisa

Curated by ChEMBL
LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataIC50:  600nMAssay Description:Binding affinity to human MDM2 expressed in Escherichia coli expression system by using (FITC)-labeled p53 peptide based fluorescence polarization co...More data for this Ligand-Target Pair
TargetProtein Mdm4(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM31197(CHEMBL211045 | Nutlin-3 | med.21724, Compound 186)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to MDMX (unknown origin) by using (FITC)-labeled p53 peptide based fluorescence polarization competitive assayMore data for this Ligand-Target Pair