Compile Data Set for Download or QSAR
maximum 50k data
Found 5 of ic50 for monomerid = 455316
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455316(US10730875, Compound 17)
Affinity DataIC50: <500nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455316(US10730875, Compound 17)
Affinity DataIC50: <500nMAssay Description:To assay JAK1 inhibition, 2 μL of IL-6 diluted at 400 ng/mL (4×) in HBSS containing 0.1% BSA was added to the treated cells. The cells were then...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455316(US10730875, Compound 17)
Affinity DataIC50:  3.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455316(US10730875, Compound 17)
Affinity DataIC50:  3.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Jn Therapeutics

US Patent
LigandPNGBDBM455316(US10730875, Compound 17)
Affinity DataIC50: >5.00E+3nMAssay Description:The in vitro inhibition of recombinant human JAKs was determined as follow.Compounds were tested in LANTHASCREEN™ time-resolved fluorescence energy t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent