Compile Data Set for Download or QSAR
maximum 50k data
Found 82 of ic50 for monomerid = 50053173
TargetBeta-lactamase(Escherichia coli)
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Escherichia coli CTX-M-15More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Salmonella enterica subsp. enterica serovar Westha...)
Centre National De R£F£Rence Des Salmonella

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of Salmonella enterica serotype Westhampton beta-lactamase CTX-M-53More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClass A beta-lactamase BCL-1(Bacillus clausii)
H�Pital De Bic�Tre

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Bacillus clausii NR beta-lactamase BCL1 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Institut Pasteur Hellenique

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  10nMAssay Description:Inhibition of Escherichia coli beta-lactamase SCO1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  17.2nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-lactamase(Proteus mirabilis)TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against Proteus vulgaris HJ33C Class-I beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against Escherichia coli HA58R Class-III TEM-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  25nMAssay Description:Inhibitory activity against beta-Lactamase enzyme derived from Escherichia coli WC3310 TEM-2More data for this Ligand-Target Pair
In DepthDetails Article
TargetBeta-lactamase SHV-1(Klebsiella pneumoniae (Enterobacteria))
Case Western Reserve University

LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataKi:  220nM IC50:  30nMpH: 7.4Assay Description:Steady state kinetics were performed on an Agilent 8453 diode array spectrophotometer in 10 mM phosphate-buffered saline (pH 7.4). IC50, defined as t...More data for this Ligand-Target Pair
TargetBeta-lactamase(Enterobacter cloacae)
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  30nMAssay Description:Inhibition of Enterobacter cloacae IMI1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
University Of Aveiro

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  30nMAssay Description:In vitro inhibitory activity against Class A (Imi-1) beta-LactamasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase BRO-1(Moraxella catarrhalis)TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  33.3nMAssay Description:Inhibitory activity against Branhamella catarrhalis 89001 Class-III BRO-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Pseudomonas luteola)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Pseudomonas luteola LAM Beta-lactamase LUT-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Citrobacter gillenii)
Bicetre Hospital

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  40nMAssay Description:Inhibition of Citrobacter gillenii CIP 106783 Beta-lactamase GIL1 expressed in Escherichia coli DH10BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
The R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  60nMAssay Description:Inhibitory activity against class A Beta-lactamase TEM isolated from Enterobacter coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-lactamase(Pseudomonas aeruginosa)
Hellenic Pasteur Institute

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of Pseudomonas aeruginosa GES-13 beta lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory concentration against TEM-1 enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Klebsiella pneumoniae)
National Institute Of Health Dr. Ricardo Jorge Av. Padre Cruz

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-72More data for this Ligand-Target Pair
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of Escherichia coli K12 TEM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Citrobacter freundii)
Universidad De Buenos Aires

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  96nMAssay Description:Inhibition of Citrobacter freundii PER2 beta lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against Class A (TEM-1) beta-LactamasesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against Beta-lactamase TEM-1 of class A enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli TEM1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Klebsiella oxytoca)TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  106nMAssay Description:Inhibitory activity against Klebsiella oxytoca HC7 Class-IV K1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase SHV-1(Klebsiella pneumoniae (Enterobacteria))
Case Western Reserve University

LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Klebsiella pneumoniae Beta-Lactamase SHV-1More data for this Ligand-Target Pair
TargetBeta-lactamase TEM(Escherichia coli)
Lek Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  130nMAssay Description:Inhibition of Escherichia coli DH5alpha beta-lactamase TEM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase SHV-1(Klebsiella pneumoniae (Enterobacteria))
Case Western Reserve University

LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  133nMAssay Description:Inhibitory activity against Escherichia coli HA208 Class-III SHV-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails PDB3D3D Structure (crystal)
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  150nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetClass D beta-lactamase(Brachyspira pilosicoli)
Institut Pasteur

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  160nMAssay Description:Inhibition of Brachyspira pilosicoli beta-lactamase OXA-63 expressed in Escherichia coli BL21 (DE3) assessed as reduction in nitrocefin hydrolysis by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Staphylococcus aureus)TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  166nMAssay Description:Inhibitory activity against Staphylococcus aureus CJ8 beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Citrobacter freundii)TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  166nMAssay Description:Inhibitory activity against Citrobacter freundii 87470 Class-I beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Morganella morganii)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  190nMAssay Description:Compound was tested for inhibition of beta-Lactamases from Morganell morgani U1627More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase SHV-1(Escherichia coli)
Nabriva Therapeutics

US Patent
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  222nMpH: 7.0 T: 2°CAssay Description:The inhibitory concentrations (IC50, [uM]) of the beta -lactamase inhibitors against purified TEM-1, SHV-1 and AmpC beta -lactamases are assessed by ...More data for this Ligand-Target Pair
TargetBeta-lactamase SHV-1(Klebsiella pneumoniae (Enterobacteria))
Case Western Reserve University

LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  222nMAssay Description:Inhibition of Escherichia coli SHV1More data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli)
Chu Clermont-Ferrand

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  240nMAssay Description:Inhibition of Escherichia coli DH5alpha beta-lactamase TEM-158More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  240nMAssay Description:Compound was tested for inhibition of Beta-lactamase from OXA-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  333nMAssay Description:Inhibitory activity against Enterobacter cloacae HC8 Class-I beta-lactamase enzyme type P99More data for this Ligand-Target Pair
In DepthDetails
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella pneumoniae)
Bicetre Hospital

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  370nMAssay Description:Inhibition of carbapenem-resistant Klebsiella pneumoniae carbepenem-hydrolyzing beta-lactamase KPC-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbapenem-hydrolyzing beta-lactamase KPC(Klebsiella pneumoniae)
Bicetre Hospital

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  374nMAssay Description:Inhibition of Klebsiella pneumoniae KPC-1 beta lactamase expressed in Escherichia coli DH5alpha by SDS-PAGEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  420nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase OXA-1(Escherichia coli (Enterobacteria))TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  432nMAssay Description:Inhibitory activity against Escherichia coli HA209 Class-V OXA-1 type beta-lactamase enzymeMore data for this Ligand-Target Pair
In DepthDetails
TargetBeta-lactamase(Staphylococcus aureus)TBA
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  500nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Staphylococcus aureus PCIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Burkholderia cenocepacia)
H�Pital De Bic�Tre

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Burkholderia cenocepacia 07-34 beta-lactamase PenB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Bacillus licheniformis)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  510nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Bacillus licheniformis 749/CMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  560nMAssay Description:Compound was tested for inhibition of Beta-lactamase from PSE-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  560nMAssay Description:Compound was tested for inhibition of Beta-lactamase from RTEM-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Pseudomonas aeruginosa (PAO1))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  820nMAssay Description:Compound was tested for inhibition of Beta-lactamase from Pseudomonas aeruginosa 18SHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Enterobacter cloacae)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50053173((2S,3S,5R)-3-Methyl-4,4,7-trioxo-3-[1,2,3]triazol-...)
Affinity DataIC50:  830nMAssay Description:Compound was tested for inhibition of Beta-lactamase fromOXA-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 82 total ) | Next | Last >>
Jump to: