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Found 17 of ic50 for monomerid = 50446376
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  3nMAssay Description:Inhibition of G9a (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  3nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of G9a (unknown origin) using biotinylated-histone H3(1-21) peptide as substrate after 3 hrs by AlphaLISA assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of G9a (unknown origin) assessed as effect on H3K9 methylation by cell based assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  11nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT1 (794 to 1294 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Promidis

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  13nMAssay Description:Inhibition of N-terminal GST tagged human recombinant EHMT2 (785 to 1210 residues) expressed in baculovirus infected Sf9 insect cells assessed as red...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  38nMAssay Description:Inhibition of GLP (unknown origin)-mediated incorporation of methyl group from [3H]-SAM into peptide substrate by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  38nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  72nMAssay Description:Inhibition of biotin-H3(1-23)K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT1(Homo sapiens (Human))
Mercachem

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  118nMAssay Description:Inhibition of GLP (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  186nMAssay Description:Binding affinity to recombinant human His-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by AlphaLI...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  207nMAssay Description:Inhibition of FL-H3K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair