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Found 7 Enz. Inhib. hit(s) with Target = 'Spindlin-1' and Ligand = 'BDBM50446376'
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  72nMAssay Description:Inhibition of biotin-H3(1-23)K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 ...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  186nMAssay Description:Binding affinity to recombinant human His-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by AlphaLI...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  207nMAssay Description:Inhibition of FL-H3K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) cell...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataIC50:  1.50E+3nMAssay Description:Displacement of trimethylated biotinylated histone H3 peptide from recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia c...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataKd:  110nMAssay Description:Inhibition of H3(1-12)K4me3 binding to recombinant human C-terminal His6-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataKd:  393nMAssay Description:Binding affinity to recombinant human His-tagged SPIN1 (26 to 262 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constan...More data for this Ligand-Target Pair
TargetSpindlin-1(Homo sapiens)
Icahn School Of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50446376(CHEMBL3109630)
Affinity DataKd:  180nMAssay Description:Binding affinity to recombinant human His-tagged SPIN1 (49 to 262 residues) expressed in Escherichia coli BL21 (DE3) assessed as dissociation constan...More data for this Ligand-Target Pair