Compile Data Set for Download or QSAR
maximum 50k data
Found 7 of ic50 for monomerid = 569236
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  0nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  0nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  0.950nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  1.90nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  4.5nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  5nMAssay Description:Compounds were prepared in the exact same manner as described in the ROCK Kinase Assay with the exception to the substrate and enzyme. The JAK 2× sub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Aerie Pharmaceuticals

US Patent
LigandPNGBDBM569236(US11427563, Compound 103)
Affinity DataIC50:  9nMAssay Description:All compounds were initially prepared as 10 mM stocks in anhydrous dimethylsulfoxide (DMSO). A 20 μl aliquot of the 10 mM solutions was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent