Compile Data Set for Download or QSAR
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Found 8 of ic50 for monomerid = 648812
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Chelation-En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK1/Cyclin B1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Luminescent ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of CDK4/Cyclin D1 assay is to evaluate the inhibition (% inhibition and IC50 values) of small molecule inhibitors by using a Chelation-En...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4/6(Homo sapiens (Human))
Iambic Therapeutics

US Patent
LigandPNGBDBM648812(8-(8,8-difluoro-2-(methyl-d3)-2,6- diazaspiro[3.4]...)
Affinity DataIC50: <200nMAssay Description:The purpose of the CDK6/Cyclin D3 assay is to evaluate the inhibition (% inhibition and IC50 values) in the presence of small molecule inhibitors by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent