Compile Data Set for Download or QSAR
maximum 50k data
Found 3 of ic50 for monomerid = 8140
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8140(N-[4-chloro-3-(trifluoromethyl)phenyl]-4-{pyrazolo...)
Affinity DataKi:  2nM IC50: <10nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8140(N-[4-chloro-3-(trifluoromethyl)phenyl]-4-{pyrazolo...)
Affinity DataIC50:  12nMpH: 7.2 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM8140(N-[4-chloro-3-(trifluoromethyl)phenyl]-4-{pyrazolo...)
Affinity DataIC50:  15nMAssay Description:The biochemical activity of compounds was determined by incubation with specific enzyme and substrate in the presence 2.5 uM ATP/ [gamma-32P] ATP. Af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed