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Found 4 Enz. Inhib. hit(s) with Target = '1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial' and Ligand = 'BDBM50370925'
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of human MBP-tagged CYP24A1 expressed in Escherichia coli using 1,25(OH)2D3 substrate in presence of bovine adrenodoxin, adrenodoxin reduc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human CYP24A1 expressed in chinese hamster V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50:  7.40nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50370925(CHEMBL1627233)
Affinity DataIC50:  28nMAssay Description:Inhibition of human CYP24 hydroxylase expressed in V79 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed