Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase 1' and Ligand = 'BDBM50117900'
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50:  96nMAssay Description:Inhibition of mouse 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50:  96nMAssay Description:In vitro inhibitory activity against mouse 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50:  96nMAssay Description:Inhibition of mouse 11beta-HSD1 using steroid as substrate incubated for 20 to 30 mins by microplate fluorimeter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50:  3.34E+3nMAssay Description:Inhibition of human 11beta-HSD1 using steroid as substrate incubated for 20 to 30 mins by microplate fluorimeter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50:  3.34E+3nMAssay Description:In vitro inhibitory activity against human 11 beta hydroxysteroid dehydrogenase type 1 using scintillation proximity assay (SPA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50:  3.34E+3nMAssay Description:Inhibition of human 11beta-HSD1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))TBA
LigandPNGBDBM50117900(3-Chloro-2-methyl-N-{4-[2-(4-methyl-piperazin-1-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Ability to convert [3H]cortisol to the tritium labeled cortisone in the presence of human 11 beta hydroxysteroid dehydrogenase type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed