Found 3 Enz. Inhib. hit(s) with Target = '11-beta-hydroxysteroid dehydrogenase type 2' and Ligand = 'BDBM50340378'
Affinity DataIC50: 7.5nMAssay Description:Inhibition of human microsomal 11beta-HSD2 assessed as inhibition of conversion of radiolabeled cortisone to radiolabeled cortisol by cell-based assa...More data for this Ligand-Target Pair
Target11-beta-hydroxysteroid dehydrogenase type 2(Mus musculus (mouse))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of mouse 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: >4.00E+3nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO-K1 cells assessed as conversion of [3H]-cortisol to [3H]-cortisone by scintillation proximity assayMore data for this Ligand-Target Pair