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Found 5 Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase type 2' and Ligand = 'BDBM50466002'
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50:  2nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate after 20 mins in presence of NAD+ by radio-flow detector bas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50:  2nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50:  2nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50:  2nMAssay Description:Inhibition of human placental microsomal fraction 17beta-HSD2 using [3H]-E2 as substrate in presence of NAD+ by radio-HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Pharmbiotec

Curated by ChEMBL
LigandPNGBDBM50466002(CHEMBL4285743)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of 17beta-HSD2 in human using MDA-MB-231 cells using [3H]-E2 as substrate after 6 hrs by cell-based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed