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Found 5 Enz. Inhib. hit(s) with Target = '17-beta-hydroxysteroid dehydrogenase type 3' and Ligand = 'BDBM50350421'
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  6nMAssay Description:Inhibition of 17Beta-HSD3 expressed in intact HEK293 cells assessed as transformation of [14C]-4-androstene-3,17-dione into [14C]-testosterone in pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  6nMAssay Description:Inhibition of 17betaHSD3 (unknown origin) transfected in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
Chu De Qu£Bec-Research Center (Chul)

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  13nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  85nMAssay Description:Inhibition of 17betaHSD3 (unknown origin) transfected in human LNCAP cells assessed as conversion of [14C]-4-androstene-3,17-dione into [14C]-testost...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
Chuq (Chul)-Research Center

Curated by ChEMBL
LigandPNGBDBM50350421(CHEMBL1813731)
Affinity DataIC50:  110nMAssay Description:Inhibition of 17-beta-HSD3 (unknown origin) expressed in human LNCaP cells using [14C]-4-androstene-3,17-dione as substrate assessed as reduction of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed