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Found 3 Enz. Inhib. hit(s) with Target = '3-oxoacyl-[acyl-carrier-protein] synthase 1' and Ligand = 'BDBM93046'
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis)
Institute For Chemical Biology & Drug Discovery

LigandPNGBDBM93046(TLM analog, 3)
Affinity DataKi:  7.10E+3nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis)
Institute For Chemical Biology & Drug Discovery

LigandPNGBDBM93046(TLM analog, 3)
Affinity DataKi:  3.57E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 1(Mycobacterium tuberculosis)
Institute For Chemical Biology & Drug Discovery

LigandPNGBDBM93046(TLM analog, 3)
Affinity DataKd:  3.30E+5nMpH: 8.5Assay Description:Binding of TLM and the TLM analogs to KasA was quantified by monitoring changes in the intrinsic tryptophan fluroescence of the enzyme using 280-nm e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed