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Found 4 Enz. Inhib. hit(s) with Target = '3-oxoacyl-[acyl-carrier-protein] synthase 3' and Ligand = 'BDBM23587'
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Enterococcus faecalis)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Streptococcus pyogenes)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  4nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Haemophilus influenzae)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  2.40E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-oxoacyl-[acyl-carrier-protein] synthase 3(Staphylococcus aureus)
Quorex Pharmaceuticals

LigandPNGBDBM23587((3-Phenoxybenzoylamino)benzoic acid deriv., 33 | 2...)
Affinity DataIC50:  3.80E+3nMpH: 7.0 T: 2°CAssay Description:The potency of FabH inhibition (IC50) was determined using [3H]- or [14C]-radiolabeled substrates. This was accomplished at fixed concentrations of a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed