Found 5 Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1' and Ligand = 'BDBM103938' Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University
Curated by ChEMBL
Brigham Young University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PDK1 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University
Curated by ChEMBL
Brigham Young University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of PDK1 (unknown origin) after 1 hr in presence of Ser/Thr-07 by fluorometric assayMore data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University
Curated by ChEMBL
Brigham Young University
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:The secondary assay was a time resolved-FRET LanthaScreen Kinase Binding Assay. (Invitrogen Corporation, Carlsbad, Calif.). This assay evaluates the...More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University
Curated by ChEMBL
Brigham Young University
Curated by ChEMBL
Affinity DataIC50: 143nMAssay Description:The primary assay for compound inhibitory activity was the ATP depletion assay using the PDKtide substrate purchase from Millipore Corporation.More data for this Ligand-Target Pair
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Brigham Young University
Curated by ChEMBL
Brigham Young University
Curated by ChEMBL
Affinity DataEC50: 76nMAssay Description:Inhibition of PDK1 mediated PI3K/Akt/mTOR pathway activation in human AN3CA cells assessed as reduction in ribosomal p70S6 protein phosphorylation af...More data for this Ligand-Target Pair
