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Found 3 Enz. Inhib. hit(s) with Target = '3-phosphoinositide-dependent protein kinase 1' and Ligand = 'BDBM11639'
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
The Ohio State University Research Foundation

US Patent
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  4.80E+4nMAssay Description:PDK-1 kinase activity This in vitro assay was performed using a PDK-1 kinase assay kit (Upstate, Lake Placid, N.Y.) according to the vendor's ins...More data for this Ligand-Target Pair
In DepthDetails US PatentDrugBank

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
The Ohio State University Research Foundation

US Patent
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of PDK1-mediated Akt activation in human PC3 cells after 2 hrs by Western blotting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
The Ohio State University Research Foundation

US Patent
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibition of recombinant PDK1 using RPRAATF as substrate by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank