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Found 10 Enz. Inhib. hit(s) with Target = '4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)' and Ligand = 'BDBM50187723'
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  0.490nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of diapophytoene desaturase in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin pigment formation after 48 hrs by spe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  320nMAssay Description:Inhibition of Staphylococcus aureus Newman Hi6-tagged CrtN expressed in Escherichia coli BL21(DE3))/pET28a::CrtN assessed as reduction in staphyloxan...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  320nMAssay Description:Inhibition of 6x-His-tagged Staphylococcus aureus diapophytoene desaturase expressed in Escherichia coli BL21 (DE3) using diapophytoene substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50187723(CHEMBL3827961)
Affinity DataIC50:  320nMAssay Description:Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21(DE3) assessed as reduction in staphyloxanthin levels u...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed