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Found 6 Enz. Inhib. hit(s) with Target = '4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)' and Ligand = 'BDBM50247168'
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50247168(CHEMBL4086008)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50247168(CHEMBL4086008)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman after 12 resistant development passages under 0.15% v/v H2O2 assessed as reduction in staphyloxant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50247168(CHEMBL4086008)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50247168(CHEMBL4086008)
Affinity DataIC50:  2nMAssay Description:Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain MW2))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50247168(CHEMBL4086008)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of CrtN in methicillin-resistant Staphylococcus aureus USA400 MW2 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming)(Staphylococcus aureus (strain Newman))
East China University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50247168(CHEMBL4086008)
Affinity DataIC50:  400nMAssay Description:Inhibition of Staphylococcus aureus Newman 6His-tagged CrtN expressed in Escherichia coli BL21 (DE3)/pET28a::CrtN assessed as reduction in staphyloxa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed