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Found 4 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 1A' and Ligand = 'BDBM50118335'
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118335(3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenatesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118335(3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...)
Affinity DataKi:  6nMAssay Description:Inhibitory activity against Beta-glucosidase from AlmondMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universidade Federal Da Para£Ba

Curated by ChEMBL
LigandPNGBDBM50118335(3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...)
Affinity DataKi:  6.03nMAssay Description:Antagonist activity at 5HT1AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Universidad De Navarra

Curated by ChEMBL
LigandPNGBDBM50118335(3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...)
Affinity DataIC50:  31.2nMAssay Description:Inhibition of (+)-8-OH-DPAT stimulated [35S]-GTP-gammaS, binding to 5-hydroxytryptamine 1A receptor in hippocampal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed