Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50001915'
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human 5HT2C receptor expressed in HEK293 cells assessed as intracellular IP3 accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]5-HT from human 5HT2CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  9nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  13nMAssay Description:Displacement of [125I]DOI from recombinant human 5-HT2C receptor expressed in HEK293 cell membranes after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  14.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at recombinant human 5-HT2C receptor expressed in HEK293E cells assessed as induction of intracellular Ca2+ levels after 90 secs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2019
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  15nMAssay Description:Activity at human 5HT2C expressed in HEK293E cells assessed as elevation of intracellular calcium by 384-FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in HEK293E cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C receptor expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]DOI from human recombinant 5HT2C expressed in HEK293E cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  26nMAssay Description:Binding to human 5HT2C receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  26nMAssay Description:Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  28nMAssay Description:Binding affinity to 5HT2C (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/3/2017
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  81.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  85.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  105nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  115nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  126nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHO K1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataEC50:  170nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  251nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Rat)
Roche Bioscience

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Arena Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001915BDBM50001915(mCPP | 1-(3-chlorophenyl)piperazine | CHEMBL478 | ...)
Affinity DataKi:  360nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMed