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Found 17 Enz. Inhib. hit(s) with Target = '72 kDa type IV collagenase' and Ligand = 'BDBM23971'
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  4.05E+4nMAssay Description:Inhibition of MMP2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  4.05E+4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of MMP2 (unknown origin) using succinylated gelatin as substrate preincubated for 10 mins before substrate addition measured after 30 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.20E+5nMAssay Description:Inhibition of human MMP-2 after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.56E+5nMAssay Description:Inhibition of recombinant MMP2 using succinylated gelatin as substrate incubated for 10 mins prior to substrate addition measured after 1 hr by UV/VI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.57E+5nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.62E+5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.63E+5nMAssay Description:Inhibition of MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Sus scrofa (Pig))
Shandong University

LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.63E+5nMAssay Description:Gelatinase A (MMP-2) and TNBS were purchased from Sigma, and the substance was synthesized as described by Vijaykumar et al. The gelatinase, substanc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  1.67E+5nMpH: 8.5 T: 2°CAssay Description:The compound samples were assayed for inhibitory activity against MMP-2 in 96-well microplates using succinylated gelatin as the substrate. The compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  2.53E+5nMAssay Description:Inhibition of MMP2 by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Shandong University

Curated by ChEMBL
LigandPNGBDBM23971((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Affinity DataIC50:  2.76E+5nMAssay Description:Inhibition of recombinant MMP-2 using succinylated gelatin as substrate incubated for 10 mins before addition of substrate measured after 60 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed