Compile Data Set for Download or QSAR
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Found 1 Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 4' and Ligand = 'BDBM471831'
TargetA disintegrin and metalloproteinase with thrombospondin motifs 4(Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM471831((5R)-5-[(2S)-3- [4-(3,4-difluoro- 5-methoxy- pheny...)
Affinity DataIC50:  75nMAssay Description:TABLE VI: The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by human ADAMTS4.For the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent