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Found 2 Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 5' and Ligand = 'BDBM50429815'
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
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Curated by ChEMBL
LigandPNGBDBM50429815(CHEMBL2337698)
Affinity DataKi:  77nMAssay Description:Inhibition of human recombinant ADAMTS5 using bovine nasal cartilage aggrecan as substrate assessed as inhibition of 1772-AGEG neopeptide formation i...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50429815(CHEMBL2337698)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant ADAMTS5 expressed in HEK293 cells using Abz-TESEwSRGAIY-Dpa-KK as substrate measured for 2 hrs by fluorometric analys...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed