Found 3 Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 5' and Ligand = 'BDBM50431947' TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant ADAMTS-5 using interglobular domain peptide of aggrecan after 60 mins by FRET assayMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Homo sapiens (Human))
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of human His-tagged ADAMTS-5 using QF-peptide as substrate by FRET methodMore data for this Ligand-Target Pair
TargetA disintegrin and metalloproteinase with thrombospondin motifs 5(Bos taurus)
Asahi Kasei Pharma
Curated by ChEMBL
Asahi Kasei Pharma
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Ex vivo inhibition of ADAMTS-5-mediated aggrecan degradation in IL-1-stimulated bovine cartilage explantMore data for this Ligand-Target Pair
