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Found 3 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor/Nucleophosmin' and Ligand = 'BDBM107057'
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM107057(US8592432, 34)
Affinity DataIC50:  20nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM107057(US8592432, 34)
Affinity DataIC50:  26nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM107057(US8592432, 34)
Affinity DataIC50:  30nMAssay Description:Inhibition NMP-ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed