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Found 3 Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11' and Ligand = 'BDBM50118348'
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50118348((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...)
Affinity DataIC50:  180nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at high...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50118348((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...)
Affinity DataIC50:  3.75E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 at low ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Novo Nordisk Research And Development

Curated by ChEMBL
LigandPNGBDBM50118348((2-Chloro-7,7-dioxo-4,7-dihydro-1,7lambda*6*-dithi...)
Affinity DataIC50:  8.99E+5nMAssay Description:Inhibition of [3H]glibenclamide binding to HEK293 cells co-expressing human Sulfonylurea receptor SUR1 and Inward rectifier K+ channel Kir6.2 without...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed