Found 4 Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50241343' TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Institute Of Clinical Pharmacology
Curated by ChEMBL
Institute Of Clinical Pharmacology
Curated by ChEMBL
Affinity DataIC50: 1.77E+4nMAssay Description:TP_TRANSPORTER: inhibition of Digoxin transepithelial transport (basal to apical) (Digoxin: 5 uM) in Caco-2 cellsMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Institute Of Clinical Pharmacology
Curated by ChEMBL
Institute Of Clinical Pharmacology
Curated by ChEMBL
Affinity DataIC50: 8.90E+4nMAssay Description:Concentration required for 50% inhibition at binding site of human P-Glycoprotein (P-gp) in one-affinity modelMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Institute Of Clinical Pharmacology
Curated by ChEMBL
Institute Of Clinical Pharmacology
Curated by ChEMBL
Affinity DataIC50: 9.12E+4nMAssay Description:Concentration required for 50% inhibition at binding site of human P-Glycoprotein (P-gp) in one-affinity modelMore data for this Ligand-Target Pair
TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Institute Of Clinical Pharmacology
Curated by ChEMBL
Institute Of Clinical Pharmacology
Curated by ChEMBL
Affinity DataIC50: 9.72E+4nMAssay Description:Concentration required for 50% inhibition at binding site of human P-Glycoprotein (P-gp) in one-affinity modelMore data for this Ligand-Target Pair
