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Found 5 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM50391781'
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50:  30nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50:  49nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50:  49nMAssay Description:Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50:  55nMAssay Description:Inhibition of rat ROMK channel expressed in HEk293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50391781(CHEMBL2146873 | US9073882, 38)
Affinity DataIC50:  110nMT: 2°CAssay Description:FluxOR Kit Components (Invitrogen F10017) FluxOR Reagent (Component A) FluxOR Assay Buffer (Component B)-10x Concentrate PowerLo...More data for this Ligand-Target Pair
In DepthDetails US Patent