Found 5 Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM50391781'
Affinity DataIC50: 30nMAssay Description:Inhibition of ROMK by electrophysiology assayMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of human ROMK expressed in HEK293 cells after 30 mins by thallium flux assayMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Rattus norvegicus (Rat))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibition of rat ROMK channel expressed in HEk293 cells assessed as inhibition of thallium efflux by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMT: 2°CAssay Description:FluxOR Kit Components (Invitrogen F10017) FluxOR Reagent (Component A) FluxOR Assay Buffer (Component B)-10x Concentrate PowerLo...More data for this Ligand-Target Pair