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Found 3 Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 1' and Ligand = 'BDBM50034371'
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  24nMAssay Description:Inhibition of rat recombinant ACC1 assessed as incorporation of [14C]bicarbonate into [14C]malonyl-CoA by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  27nMAssay Description:Inhibition of human recombinant ACC1 assessed as incorporation of [14C]bicarbonate into [14C]malonyl-CoA by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50034371(CHEMBL3359265)
Affinity DataIC50:  98nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed