Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 1' and Ligand = 'BDBM50439637'
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  17nMAssay Description:Inhibition of rat recombinant ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human C-terminal His-tagged ACC1 (1 to 2383 residues) expressed in baculovirus infected Sf9 insect cells preincubated for 1...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  19nMAssay Description:Inhibition of human ACC1 using acetyl-CoA as substrate assessed as [14C]malonyl-CoA synthesis preincubated for 10 mins prior to substrate addition me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Xuzhou Medical University

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  111nMAssay Description:Inhibition of human recombinant ACC1 after 1 hr by transcreener assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed