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Found 3 Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 2' and Ligand = 'BDBM50446514'
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of human ACC2 expressed in CHOK1 cells assessed as acetylCoA to malonylCoA conversion after 1 hr by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)
Affinity DataIC50:  54nMAssay Description:Inhibition of human ACC2 assessed as acetylCoA to malonylCoA conversion after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Mus musculus)
Amgen

Curated by ChEMBL
LigandPNGBDBM50446514(CHEMBL3110076)
Affinity DataIC50:  89nMAssay Description:Inhibition of mouse ACC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed