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Found 4 Enz. Inhib. hit(s) with Target = 'Activin receptor type-1 [172-499]' and Ligand = 'BDBM451773'
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451773(US10710980, Example 5 | US10947218, Example 5)
Affinity DataIC50:  7nMAssay Description:A kinase selectivity panel which measures autophosphorylation using the ADP-Glo Kinase Assay (Promega, V9101) was set-up for wild-type ALK2 (aa172-49...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451773(US10710980, Example 5 | US10947218, Example 5)
Affinity DataIC50:  7nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451773(US10710980, Example 5 | US10947218, Example 5)
Affinity DataIC50:  10nMAssay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for wild-type ALK2 (aa172-499), ALK2 FOP mutant (aa172-499 R20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451773(US10710980, Example 5 | US10947218, Example 5)
Affinity DataIC50:  10nMAssay Description:In the applied method, this separation takes place inside a chip that contains a complex capillary system for simultaneous analysis of 12 samples (“1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent