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Found 2 Enz. Inhib. hit(s) with Target = 'Acyl-CoA desaturase 1' and Ligand = 'BDBM50448657'
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50448657(CHEMBL3127530 | US9102669, 29)
Affinity DataIC50:  7nMT: 2°CAssay Description:The SCD1 enzymatic assay was done in a volume of 50 μL using 10 μg of RLM (prepared as described above) in a 96-well polypropylene plate (e...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAcyl-CoA desaturase 1(Rattus norvegicus (Rat))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50448657(CHEMBL3127530 | US9102669, 29)
Affinity DataIC50:  22nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using stearoyl-[9,10-3H]-CoA as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed