Found 12 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM50053929' TargetAdenosine receptor A1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Binding affinity to wild type A1R (unknown origin) expressed in CHO-K1 cells assessed as equilibrium binding affinity constant by nanoBRET assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataKi: 51nMAssay Description:Displacement of CA200645 from NLuc human A1 receptor expressed in HEK293 cells assessed as inhibition constant by NanoBRET binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 52.7nMAssay Description:Binding affinity was determined in radioligand binding assay at rat brain adenosine A1 receptor vs [3H]-R-PIAMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Displacement of [3H]CCPA from rat adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 53nMAssay Description:Displacement of [3H]-DPCPX from Adenosine A1 receptor of rat brain membranesMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataKi: 231nMAssay Description:Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by gamma counterMore data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Displacement of specific [3H]-(R)-PIA binding at adenosine A1 receptor from rat brain membranes.More data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Displacement of [3H]-¿-PIA from Adenosine A1 receptor of rat cerebral cortex membranesMore data for this Ligand-Target Pair
Affinity DataKi: 305nMAssay Description:Inhibition of [3H]-DPCPX binding to rat Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Antagonist activity at wild type A1R (unknown origin) expressed in CHO-K1 cells assessed as inhibition of NECA reduced forskolin stimulated cAMP accu...More data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding affinity to Nluc-A1R (unknown origin) expressed in HEK293 cells by nanoBRET assayMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Homo sapiens (Human))
National And Kapodistrian University Of Athens
Curated by ChEMBL
National And Kapodistrian University Of Athens
Curated by ChEMBL
Affinity DataEC50: 48nMAssay Description:Antagonist activity at human wild type A1R expressed in CHO-K1 cells assessed as inhibition of forskolin/ NECA-stimulated cAMP accumulation by measur...More data for this Ligand-Target Pair
