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Found 3 Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2a' and Ligand = 'BDBM50553401'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50553401(CHEMBL4778265)
Affinity DataKi:  0.110nMAssay Description:Inhibition of FRET-labelled CA200645 binding to human adenosine 2A receptor expressed in CHO cells incubated for 2 hr by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50553401(CHEMBL4778265)
Affinity DataIC50:  77nMAssay Description:Antagonist activity at adenosine 2A receptor in human PBMC assessed as reversal of NECA/CD3/CD28-stimulated IL-2 release incubated for 24 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Fudan University

Curated by ChEMBL
LigandPNGBDBM50553401(CHEMBL4778265)
Affinity DataIC50: >200nMAssay Description:Antagonist activity at adenosine 2A receptor in human blood assessed as reversal of NECA/LPS-stimulated TNF-alpha release incubated for 5 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed