Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with Target = 'Aldo-keto reductase family 1 member A1' and Ligand = 'BDBM50009832'
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 0.480nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with D-glucose as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 28nMAssay Description:Inhibitory activity was measured against renal inner medulla aldehyde reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 3.65E+3nMAssay Description:Inhibitory activity was measured against pig kidney aldehyde reductase in the presence of 1 uM compound with 3-pyridine carboxaldehyde as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory activity was measured against whole kidney aldehyde reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 3.54E+4nMAssay Description:Inhibitory activity was measured against rat lens aldose reductase in the presence of 1 uM compound with DL-glyceraldehyde as substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 2.10E+5nMAssay Description:Inhibitory activity was measured against renal outer medulla aldehyde reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
LigandPNGBDBM50009832(CHEMBL269550 | 1-Benzyl-4-hydroxy-5-oxo-2,5-dihydr...)
Affinity DataIC50: 4.80E+5nMAssay Description:Inhibitory activity was measured against renal cortex aldehyde reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed