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Found 4 Enz. Inhib. hit(s) with Target = 'Alpha-1B adrenergic receptor' and Ligand = 'BDBM50421580'
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421580(CHEMBL117248)
Affinity DataKi:  66nMAssay Description:Affinity to human Alpha-1B adrenergic receptor determined by radioligand binding techniques from rat-1 fibroblasts membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421580(CHEMBL117248)
Affinity DataIC50:  219nMAssay Description:In vitro binding affinity against cloned human alpha-1B-adrenoreceptor receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421580(CHEMBL117248)
Affinity DataEC50:  2nMAssay Description:Activation of human alpha-1B adrenergic receptors expressed in rat-1 fibroblastsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1B adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50421580(CHEMBL117248)
Affinity DataEC50:  2.20nMAssay Description:Agonist potency at alpha-1b adrenoceptors assayed in rat-1 fibroblasts expressing human alpha-1bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed